PGXperts PRiM
Personalized Risk management in the Medication Process
PGXperts PRiM identifies potential risks of the patient’s current medication in the clinical routine based on the available patient data. The goal is to enable personalized medication and increase drug therapy safety.
References
Benefits
Features
KHZG
Cooperations
Increasing demands on quality and efficiency require innovative solutions, seamless integration into the existing IT landscape and direct connection to the telematics infrastructure. Equally important is eligibility for KHZG (Hospital Future Act) funding to ensure cost effective implementation.
Hospitals trust us nationwide
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Personalized
Complex medication always under control
Patient safety is the top priority when prescribing medication, as side effects or treatment failure can have serious consequences.
Therefore, it is crucial to consider the dosage and interactions of the medications being taken, as well as individual risk factors such as allergies, lab values, and genetic factors.
Efficient
Everyone benefits from optimized medication processes
With our digital drug therapy safety pathway, we guide users safely through the medication process, reducing the workload of medical staff. By avoiding medication risks, not only can patient well-being be improved, but potential follow-up costs can also be prevented.
Intuitive
User-friendly design that delights
Users are guided step by step through the medication process. All essential functions are easily accessible on the user interface, and the clear classification of interaction severity provides additional clarity.
Interoperabel
Seamless integration into your IT infrastructure
Our open interfaces ensure efficient integration into your IT landscape by supporting HL7 and FHIR standards. The software is web-based and installed locally on your servers. The interface to the telematics infrastructure enables access to the electronic patient file (ePA) for the creation of the electronic medication plan (eMP) and e-prescriptions.
No licensing fees for interfaces
Including free interface maintenance
Become a pioneer of Personalized Medication
Hospital Future Act
Take advantage of the government KHZG (Hospital Future Act) funding!
PGXperts PRiM is integrated into the electronic patient chart VMobil by ADVANOVA GmbH. Together, we meet the requirements of KHZG funding criterion 5: Digital Medication Management.
Discover PGXperts PRiM
Review of drug therapy safety risks
With the drug therapy safety check, users can verify interactions between medications, foods, genetics, and risk factors such as age, gender, allergies, or kidney function.
Available anytime and anywhere
Thanks to the web-based system, users across the entire hospital network can conveniently access PGXperts PRiM without the need for additional software installation.
Personalized medication with pharmacogenetics
Pharmacogenetics enables the prediction of an individual's response to a medication based on their genetic traits.
Supports the prescription of e-prescriptions
PGXperts PRiM supports the prescription of e-prescriptions according to the guidelines of the National Association of Statutory Health Insurance Physicians and Gematik.
EN ISO 13485 certified QMS
PGXperts PRiM meets the highest standards of quality and reliability with a certified quality management system.
Integration into the telematics infrastructure
Access to the electronic patient record (ePA) enables the creation of medication plans (BMP and eMP) as well as the prescription of e-prescriptions.
Cooperation partner
PGXperts PRiM as an integrated drug therapy safety solution
PGXperts PRiM is compatible with a wide range of healthcare IT solutions. As an drug therapy safety partner, we are integrated into the digital care and treatment documentation VMobil by ADVANOVA.
Pharmacogenetics is the key to Personalized Medication
Pharmacogenetics studies how our genes influence the effectiveness and safety of medications. It enables safe and effective drug therapy tailored to the individual genetics of each patient.
Martin Gröne
Head of Sales & Business Development – ICx
Contact
Efficient drug therapy begins with a consultation – no strings attached!
We would be happy to introduce you to the features and benefits of PGXperts PRiM. Schedule an appointment today with your personal consultant.
In 5 Steps to Personalized Medication with the PGXperts PGxProfile
The PGxProfile helps you consider your patients’ genetically determined risks in the prescription process and avoid adverse drug reactions by personalizing the choice and dosage of medication.
It contains the results of the pharmacogenetic analysis with all the analyzed gene variants and their influence on the efficacy and tolerability of specific medications, including clinical consequences and actions.
1. Conduct a consultation with the patient
2. Collect a 2-5 ml EDTA blood sample
3. Send documentation and blood sample to the laboratory
4. Scan PGxProfile into PGXperts PRiM
5. Educate the patient and personalize the medication
Benefits of PGxProfile
Benefits for the hospital
Improved therapy response time through rapid dosage adjustments.
Take a leading position in personalized medication in clinical routine
Reduces readmission rates and shortens hospital stay duration
Additional revenue potential through PGx testing
Benefits for the patients
The right therapy and treatment without trial and error
Lower risk of adverse drug reactions (ADR)
Better response to therapy and fewer side effects
Patients benefit from a PGxProfile for a lifetime
Integration into the digital care and treatment documentation VMobil
PGXperts PRiM and VMobil
Reliable medication management
The mobile electronic patient pathway VMobil from ADVANOVA GmbH was specifically developed for clinical practice. Aiming to reduce medication errors and avoidable risks for patients in drug therapy, PGXperts PRiM enhances the system with a range of features:
Medication anamnesis and transition to hospital medication
Creation of discharge medication (including e-prescription)
AMTS check at every step along the medication process
Supporting pharmacogenetic end-to-end process
Polypharmacy patient*
Mrs Elisabeth Schmidt (74) is hospitalized due to severe pneumonia.
She reports an ulcer in her mouth and an unexplained haematoma on her lower leg.
In addition to rheumatoid arthritis, she suffers from high blood pressure and her uric acid levels are elevated.
Medication anamnesis
by scanning the medication plan that the patient has brought with them.
All the information it contains is transferred automatically into PGXperts PRiM.
Hospital medication
Ramipril is replaced by Enalapril.
She prescribes the antibiotic Ampicillin/Sulbactam i.v. to treat the pneumonia.
She advises Mrs Schmidt to avoid milk while taking Azathioprine and to avoid eating grapefruit and liquorice.
Drug interaction
She discovers a serious interaction between Azathioprine and Allopurinol, which can lead to increased liver values and blood disorders.
There is also a risk of severe skin reactions due to a potential pharmacogenetic effect.
For this reason, she switches Allopurinol to Benzbromarone 20mg daily, slowly increasing to 100mg.
Pharmacogenetic effect
She then orders genotyping, the results of which show reduced TPMT activity.
As a result Dr Müller reduces the dose.
Extended risk factor
Dr Müller switches his clinic medication from Bisoprolol to Nebivolol due to a previous severe pollen allergy in order to minimise the risk of a severe allergic reaction.
Discharge medication
1) Medication anamnesis
Dr Müller records the patient´s medication history
She records the current medication by scanning the patients medication plan.
All the information it contains is transferred automatically into PGXperts PRiM.
2) Hospital medication
Dr Müller changes the medication to the hospital formulary, which is stored in PGXperts PRiM.
Ramipril is replaced by Enalapril.
She advises Mrs Schmidt to avoid milk while taking Azathioprine and to avoid eating grapefruit and liquorice.
She prescribes the antibiotic Ampicillin/Sulbactam i.v. to treat the pneumonia.
Dr Müller checks the medication for drug therapy safety risks with PGXperts PRiM.
She discovers a serious interaction between Azathioprine and Allopurinol, which can lead to increased liver values and blood disorders.
There is also a risk of severe skin reactions due to a potential pharmacogenetic effect.
For this reason, she switches Allopurinol to Benzbromarone 20mg daily, slowly increasing to 100mg.
4) Pharmacogenetic effect
Dr Müller is informed that the FDA recommends genetic testing before administering the high-risk drug Azathioprine due to its Myelotoxicity.
She then orders genotyping, the results of which show reduced TPMT activity.
As a result Dr Müller reduces the dose.
5) Extended risk factor
PGXperts PRiM accesses historical and current treatment data.
Dr Müller switches from Bisoprolol to Nebivolol in the hospital medication due to a previous severe pollen allergy in order to minimise the risk of a severe allergic reaction.
6) Discharge medication
Mrs Schmidt recovers from the pneumonia within a few days and is discharged from hospital.
Dr Müller expects that by reducing the dose of Azathioprine, the mouth ulcer and haematoma will subside in the near future.
The discharge medication is created in PGXperts PRiM and automatically transferred to the doctor’s discharge summary letter.
Dr Müller creates a new electronic prescription and an eMP.
*Disclaimer: All scenarios depicted are purely fictitious and are for illustrative purposes only.
Similarities with real situations are purely coincidental and not intentional.