{"id":51373,"date":"2024-12-05T15:08:58","date_gmt":"2024-12-05T14:08:58","guid":{"rendered":"https:\/\/pgxperts.com\/?page_id=51373"},"modified":"2025-12-09T10:07:10","modified_gmt":"2025-12-09T09:07:10","slug":"pharmakogenetik","status":"publish","type":"page","link":"https:\/\/pgxperts.com\/en\/pharmacogenetics\/","title":{"rendered":"07-Pharmakogenetik_B"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; admin_label=&#8221;Section&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(36,149,208,0.1)&#8221; custom_padding=&#8221;115px||0px||false|false&#8221; custom_padding_tablet=&#8221;25px||50px||false|false&#8221; custom_padding_phone=&#8221;25px||5px||false|false&#8221; background_enable_image_tablet=&#8221;off&#8221; background_enable_image_phone=&#8221;off&#8221; da_disable_devices=&#8221;off|off|off&#8221; border_color_bottom=&#8221;rgba(135,137,136,0.21)&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; width_tablet=&#8221;&#8221; width_phone=&#8221;&#8221; width_last_edited=&#8221;on|desktop&#8221; custom_margin=&#8221;|auto|75px|auto|false|false&#8221; custom_margin_tablet=&#8221;||40px||false|false&#8221; custom_margin_phone=&#8221;||50px||false|false&#8221; custom_margin_last_edited=&#8221;on|tablet&#8221; custom_padding=&#8221;0px||0px|||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.24.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/pgxperts.com\/wp-content\/uploads\/2025\/05\/PGXperts_Fragezeichen_transparent_ausgefuellt_72ppi_Crop.png&#8221; alt=&#8221;Questionmark for medication&#8221; title_text=&#8221;Questionmark for medication&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;50%&#8221; module_alignment=&#8221;center&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_css_main_element=&#8221;margin: auto&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text content_tablet=&#8221;<\/p>\n<h1>Personalized<br \/>\nmedication management<\/h1>\n<p>&#8221; content_phone=&#8221;<\/p>\n<h1>Personalized<br \/>\nmedication management<\/h1>\n<p>&#8221; content_last_edited=&#8221;off|desktop&#8221; disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;|700|||||||&#8221; text_text_color=&#8221;#2495D0&#8243; text_font_size=&#8221;26px&#8221; header_font=&#8221;Arial||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_font=&#8221;Arial|700|||||||&#8221; header_2_text_color=&#8221;#0A0A0A&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;center&#8221; header_3_text_color=&#8221;#0A0A0A&#8221; header_3_font_size=&#8221;26px&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||5px||false|false&#8221; custom_padding=&#8221;|||&#8221; text_font_size_tablet=&#8221;26px&#8221; text_font_size_phone=&#8221;26px&#8221; text_font_size_last_edited=&#8221;off|tablet&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;22px&#8221; header_2_font_size_last_edited=&#8221;on|desktop&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; header_font_size__hover=&#8221;30px&#8221; header_font_size__hover_enabled=&#8221;30px&#8221; header_letter_spacing__hover=&#8221;0px&#8221; header_letter_spacing__hover_enabled=&#8221;0px&#8221; header_text_shadow_style__hover=&#8221;none&#8221; header_text_shadow_style__hover_enabled=&#8221;none&#8221; header_text_shadow_color__hover=&#8221;rgba(0,0,0,0.4)&#8221; header_text_shadow_color__hover_enabled=&#8221;rgba(0,0,0,0.4)&#8221;]<\/p>\n<p>The future of drug therapy<\/p>\n<p>[\/et_pb_text][et_pb_text disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial||||||||&#8221; header_font=&#8221;Arial||||||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#0A0A0A&#8221; header_font_size=&#8221;44px&#8221; header_line_height=&#8221;1.1em&#8221; header_2_font=&#8221;Arial|600|||||||&#8221; header_2_line_height=&#8221;1.2em&#8221; header_3_font=&#8221;Arial|700|||||||&#8221; header_3_text_color=&#8221;#FFFFFF&#8221; header_3_font_size=&#8221;44px&#8221; header_3_line_height=&#8221;1em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; min_height=&#8221;7.6px&#8221; custom_margin=&#8221;0px||16px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; header_font_size_tablet=&#8221;44px&#8221; header_font_size_phone=&#8221;32px&#8221; header_font_size_last_edited=&#8221;on|phone&#8221; header_3_font_size_tablet=&#8221;44px&#8221; header_3_font_size_phone=&#8221;38px&#8221; header_3_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1 style=\"text-align: left;\">Pharmacogenetics (PGx)<\/h1>\n<p>[\/et_pb_text][et_pb_text disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;18px&#8221; text_orientation=&#8221;center&#8221; module_alignment=&#8221;left&#8221; min_height=&#8221;110.8px&#8221; custom_margin=&#8221;||1px||false|false&#8221; text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: left;\">Every human being is unique \u2013 and their response to medication is just as individual. Pharmacogenetics investigates how our genes influence the effect of drugs. <\/p>\n<p style=\"text-align: left;\">This knowledge enables personalized medication, whereby the right medication in the appropriate dosage can be selected for each individual patient. This makes therapies more effective and reduces side effects. <\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||0px|||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_divider color=&#8221;#878988&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; text_text_color__hover=&#8221;#2495D0&#8243; text_text_color__hover_enabled=&#8221;on|desktop&#8221; text_font_size__hover=&#8221;17px&#8221; text_font_size__hover_enabled=&#8221;on|hover&#8221; transform_styles__hover_enabled=&#8221;off|desktop&#8221; transform_scale__hover=&#8221;103%|103%&#8221; transform_scale__hover_enabled=&#8221;off|desktop&#8221; transform_translate__hover_enabled=&#8221;off|desktop&#8221; 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text_text_color=&#8221;#878988&#8243; text_orientation=&#8221;center&#8221; link_option_url=&#8221;#Explanation&#8221; text_line_height_tablet=&#8221;&#8221; text_line_height_phone=&#8221;0.7em&#8221; text_line_height_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221; text_text_color__hover_enabled=&#8221;on|desktop&#8221; text_text_color__hover=&#8221;#2495D0&#8243; text_font_size__hover=&#8221;16px&#8221; text_font_size__hover_enabled=&#8221;on|hover&#8221; transform_styles__hover_enabled=&#8221;on|hover&#8221; transform_scale__hover=&#8221;103%|103%&#8221; transform_scale__hover_enabled=&#8221;on|hover&#8221; transform_translate__hover_enabled=&#8221;on|hover&#8221; transform_rotate__hover_enabled=&#8221;on|hover&#8221; transform_skew__hover_enabled=&#8221;on|hover&#8221; transform_origin__hover_enabled=&#8221;on|hover&#8221;]<\/p>\n<p>Explanation<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; 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Usage<br \/>\n[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#878988&#8243; text_orientation=&#8221;center&#8221; link_option_url=&#8221;#Metabolization&#8221; text_line_height_tablet=&#8221;&#8221; text_line_height_phone=&#8221;0.7em&#8221; text_line_height_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221; text_text_color__hover_enabled=&#8221;on|desktop&#8221; text_text_color__hover=&#8221;#2495D0&#8243; text_font_size__hover=&#8221;16px&#8221; text_font_size__hover_enabled=&#8221;on|hover&#8221; transform_styles__hover_enabled=&#8221;on|hover&#8221; transform_scale__hover=&#8221;103%|103%&#8221; transform_scale__hover_enabled=&#8221;on|hover&#8221; transform_translate__hover_enabled=&#8221;on|hover&#8221; transform_rotate__hover_enabled=&#8221;on|hover&#8221; transform_skew__hover_enabled=&#8221;on|hover&#8221; transform_origin__hover_enabled=&#8221;on|hover&#8221;]Metabolization<br \/>\n[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#878988&#8243; text_orientation=&#8221;center&#8221; link_option_url=&#8221;#benefits&#8221; text_line_height_tablet=&#8221;&#8221; text_line_height_phone=&#8221;0.7em&#8221; text_line_height_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221; text_text_color__hover_enabled=&#8221;on|desktop&#8221; text_text_color__hover=&#8221;#2495D0&#8243; text_font_size__hover=&#8221;16px&#8221; text_font_size__hover_enabled=&#8221;on|hover&#8221; transform_styles__hover_enabled=&#8221;on|hover&#8221; 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da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row column_structure=&#8221;3_5,2_5&#8243; make_equal=&#8221;on&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221; disabled_on=&#8221;off|off|off&#8221; module_class=&#8221;custom_row&#8221; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; vertical_offset=&#8221;0px&#8221; custom_margin=&#8221;|auto|-1px|auto|false|false&#8221; custom_padding=&#8221;142px||0px||false|false&#8221; custom_padding_tablet=&#8221;50px||||false|false&#8221; custom_padding_phone=&#8221;50px||||false|false&#8221; custom_css_free_form=&#8221;@media all and (max-width: 980px) {||\/*** wrap row in a flex box ***\/||.custom_row {|| display: -webkit-box;|| display: -moz-box;|| display: -ms-flexbox;|| display: -webkit-flex;|| display: flex;||-webkit-flex-wrap: wrap; \/* Safari 6.1+ *\/||flex-wrap: wrap;||}|| ||\/*** custom classes that will designate the order of columns in the flex box row ***\/||.first-on-mobile {||-webkit-order: 1;||order: 1;||}|| ||.second-on-mobile {||-webkit-order: 2;||order: 2;||}|| ||.third-on-mobile {||-webkit-order: 3;||order: 3;||}|| ||.fourth-on-mobile {||-webkit-order: 4;||order: 4;||}||\/*** add margin to last column ***\/||.custom_row:last-child .et_pb_column:last-child {||margin-bottom: 30px;||}|| ||}&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_css_main_element=&#8221;margin: auto&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text content_tablet=&#8221;<\/p>\n<h2 style=%22text-align: left;%22><strong>Our genetics effect the<span style=%22color: #2495d0;%22> efficacy<\/span> and <span style=%22color: #2495d0;%22>safety<\/span><strong> of medications<\/strong><\/h2>\n<p>&#8221; content_phone=&#8221;<\/p>\n<h2 style=%22text-align: left;%22><strong>Our genetics effect the <span style=%22color: #2495d0;%22>efficacy<\/span> and <span style=%22color: #2495d0;%22>safety<\/span> <strong>of medications<\/strong><\/strong><\/h2>\n<p>&#8221; content_last_edited=&#8221;on|phone&#8221; disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;Arial||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_font_size=&#8221;56px&#8221; 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header_2_font_size_last_edited=&#8221;on|phone&#8221; header_3_font_size_tablet=&#8221;44px&#8221; header_3_font_size_phone=&#8221;38px&#8221; header_3_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; header_font_size__hover=&#8221;30px&#8221; header_font_size__hover_enabled=&#8221;30px&#8221; header_letter_spacing__hover=&#8221;0px&#8221; header_letter_spacing__hover_enabled=&#8221;0px&#8221; header_text_shadow_style__hover=&#8221;none&#8221; header_text_shadow_style__hover_enabled=&#8221;none&#8221; header_text_shadow_color__hover=&#8221;rgba(0,0,0,0.4)&#8221; header_text_shadow_color__hover_enabled=&#8221;rgba(0,0,0,0.4)&#8221;]<\/p>\n<h2 style=\"text-align: left;\"><strong>Our genetics effect the <span style=\"color: #2495d0;\">efficacy<\/span> and <span style=\"color: #2495d0;\">safety<\/span><\/strong><strong> of medications<\/strong><\/h2>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.27.0&#8243; 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text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: left;\">Genetic differences among patients are mostly not taken into account in today\u2019s (<strong>one-size-fits-all<\/strong>) drug therapy.<\/p>\n<p style=\"text-align: left;\"><span data-teams=\"true\">Therefore, it is common for a medication to have the desired therapeutic effect for one patient, while for another patient, it may lead to treatment failure or adverse drug reactions (ADR).<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; admin_label=&#8221;Section&#8221; module_id=&#8221;Explanation&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;50px|||||&#8221; custom_padding_tablet=&#8221;50px|||||&#8221; custom_padding_phone=&#8221;30px||||false|false&#8221; da_popup_slug=&#8221;Erkl-rung&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;|auto|30px|auto||&#8221; custom_padding=&#8221;40px||40px|||&#8221; border_radii=&#8221;on|15px|15px|15px|15px&#8221; border_width_all=&#8221;2px&#8221; border_color_all=&#8221;rgba(135,137,136,0.18)&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text content_tablet=&#8221;<\/p>\n<h3>Optimizing complex pharmacotherapy<\/h3>\n<p>&#8221; content_phone=&#8221;<\/p>\n<h3>Optimizing complex pharmacotherapy<\/h3>\n<p>&#8221; content_last_edited=&#8221;off|desktop&#8221; disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_font=&#8221;Barlow||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_font=&#8221;Arial|700|||||||&#8221; header_2_text_color=&#8221;#0A0A0A&#8221; header_2_font_size=&#8221;44px&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;center&#8221; header_3_text_color=&#8221;#0A0A0A&#8221; header_3_font_size=&#8221;44px&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||-1px||false|false&#8221; custom_padding=&#8221;|||&#8221; header_2_font_size_tablet=&#8221;44px&#8221; header_2_font_size_phone=&#8221;22px&#8221; header_2_font_size_last_edited=&#8221;on|phone&#8221; header_3_font_size_tablet=&#8221;44px&#8221; header_3_font_size_phone=&#8221;28px&#8221; header_3_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; header_font_size__hover=&#8221;30px&#8221; header_font_size__hover_enabled=&#8221;30px&#8221; header_letter_spacing__hover=&#8221;0px&#8221; header_letter_spacing__hover_enabled=&#8221;0px&#8221; header_text_shadow_style__hover=&#8221;none&#8221; header_text_shadow_style__hover_enabled=&#8221;none&#8221; header_text_shadow_color__hover=&#8221;rgba(0,0,0,0.4)&#8221; header_text_shadow_color__hover_enabled=&#8221;rgba(0,0,0,0.4)&#8221;]<\/p>\n<h3 style=\"text-align: center;\"><span style=\"color: #2495d0;\">PHARMACOGENETICS<\/span><\/h3>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Times New Roman||||||||&#8221; text_text_color=&#8221;#2495D0&#8243; text_font_size=&#8221;22px&#8221; header_font=&#8221;|700||on|||||&#8221; header_font_size=&#8221;44px&#8221; header_line_height=&#8221;1em&#8221; header_2_font=&#8221;|700|||||||&#8221; custom_margin=&#8221;-1px||||false|false&#8221; custom_margin_tablet=&#8221;-1px||||false|false&#8221; custom_margin_phone=&#8221;0px||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px|15px||15px|false|false&#8221; text_font_size_tablet=&#8221;19px&#8221; text_font_size_phone=&#8221;17px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: center;\"><em>effect of medication taking genetic characteristics into account<\/em><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;2_5,3_5&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;2&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||35px|||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(36,149,208,0.1)&#8221; custom_padding=&#8221;30px|30px|30px|30px|false|false&#8221; border_radii=&#8221;on|15px|15px|15px|15px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_font=&#8221;Arial||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_font=&#8221;Arial|700|||||||&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#0A0A0A&#8221; header_2_font_size=&#8221;26.1px&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;left&#8221; header_3_text_color=&#8221;#0A0A0A&#8221; header_3_font_size=&#8221;26px&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||||false|false&#8221; custom_margin_tablet=&#8221;0px||5px||false|false&#8221; custom_margin_phone=&#8221;0px||15px||false|false&#8221; custom_margin_last_edited=&#8221;on|tablet&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;22px&#8221; header_2_font_size_last_edited=&#8221;on|desktop&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>What is pharmacogenetics?<\/h3>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;18px&#8221; header_font=&#8221;|700||on|||||&#8221; header_font_size=&#8221;44px&#8221; header_line_height=&#8221;1em&#8221; header_2_font=&#8221;|700|||||||&#8221; custom_margin=&#8221;-1px||||false|false&#8221; custom_margin_tablet=&#8221;-1px||||false|false&#8221; custom_margin_phone=&#8221;0px||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||||false|false&#8221; text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span data-teams=\"true\">Pharmacogenetics (PGx) investigates the influence of different <strong>genetic variants<\/strong> in a patient on the metabolism of drugs. <\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(36,149,208,0.1)&#8221; custom_padding=&#8221;30px|30px|30px|30px|false|false&#8221; border_radii=&#8221;on|15px|15px|15px|15px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_font=&#8221;Arial||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_font=&#8221;Arial|700|||||||&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#0A0A0A&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;left&#8221; header_3_text_color=&#8221;#0A0A0A&#8221; header_3_font_size=&#8221;26px&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||5px||false|false&#8221; custom_padding=&#8221;||0px||false|false&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;22px&#8221; header_2_font_size_last_edited=&#8221;on|desktop&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3 style=\"text-align: left;\">How do genetic variants influence the effect of drugs?<\/h3>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;18px&#8221; header_font=&#8221;|700||on|||||&#8221; header_font_size=&#8221;44px&#8221; header_line_height=&#8221;1em&#8221; header_2_font=&#8221;|700|||||||&#8221; text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Enzymes, transport proteins, and receptors regulate the absorption, distribution, and excretion of drugs in the body. Genetic differences influence both their quantity and function, and thus the <strong>speed<\/strong> at which drugs take effect and are broken down. <\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;2&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px|||||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; border_radii=&#8221;on|15px|15px|15px|15px&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_spread=&#8221;-5px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/pgxperts.com\/wp-content\/uploads\/2024\/10\/Pharmakogenetik_Historie.jpg&#8221; title_text=&#8221;Pharmakogenetik_Historie&#8221; _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; width_tablet=&#8221;100%&#8221; width_phone=&#8221;100%&#8221; width_last_edited=&#8221;on|tablet&#8221; max_width_phone=&#8221;600px&#8221; max_width_last_edited=&#8221;off|phone&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_font=&#8221;Arial||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_font=&#8221;Arial|700|||||||&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#0A0A0A&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;left&#8221; header_3_text_color=&#8221;#0A0A0A&#8221; header_3_font_size=&#8221;26px&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||5px||false|false&#8221; custom_padding=&#8221;|30px|0px|30px|false|false&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;22px&#8221; header_2_font_size_last_edited=&#8221;on|desktop&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Since when has pharmacogenetics existed?<\/h3>\n<p>[\/et_pb_text][et_pb_text content_last_edited=&#8221;off|desktop&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial||||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;18px&#8221; header_font=&#8221;Arial||||||||&#8221; text_orientation=&#8221;center&#8221; custom_margin=&#8221;5px||||false|false&#8221; custom_padding=&#8221;|30px||30px|false|false&#8221; custom_padding_tablet=&#8221;|25px||25px|false|false&#8221; custom_padding_phone=&#8221;|25px||25px|false|false&#8221; custom_padding_last_edited=&#8221;off|desktop&#8221; text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: left;\">The term pharmacogenetics was coined in 1959 by Friedrich Vogel, who laid the foundation for a new field of research and personalized medication.<\/p>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;#history&#8221; button_text=&#8221;Find out more&#8221; button_alignment=&#8221;left&#8221; disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_size=&#8221;18px&#8221; button_text_color=&#8221;#FFFFFF&#8221; button_bg_color=&#8221;#2495D0&#8243; button_border_width=&#8221;0px&#8221; button_font=&#8221;Arial||||||||&#8221; custom_margin=&#8221;||35px|30px|false|false&#8221; custom_padding=&#8221;||||false|false&#8221; button_text_size_tablet=&#8221;18px&#8221; button_text_size_phone=&#8221;16px&#8221; button_text_size_last_edited=&#8221;on|phone&#8221; custom_css_main_element=&#8221;white-space: nowrap;||margin:auto;&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_spread=&#8221;-8px&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; border_radii=&#8221;on|15px|15px|15px|15px&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_spread=&#8221;-5px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/pgxperts.com\/wp-content\/uploads\/2024\/10\/WasWirdUntersucht.jpg&#8221; title_text=&#8221;What is examined?&#8221; _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; width_tablet=&#8221;100%&#8221; width_phone=&#8221;100%&#8221; width_last_edited=&#8221;on|tablet&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_font=&#8221;Arial||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_font=&#8221;Arial|700|||||||&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#0A0A0A&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;left&#8221; header_3_text_color=&#8221;#0A0A0A&#8221; header_3_font_size=&#8221;26px&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||5px||false|false&#8221; custom_padding=&#8221;|30px|0px|30px|false|false&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;22px&#8221; header_2_font_size_last_edited=&#8221;on|desktop&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>What is analysed in pharmacogenetics?<\/h3>\n<p>[\/et_pb_text][et_pb_text content_last_edited=&#8221;off|desktop&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial||||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;18px&#8221; header_font=&#8221;Arial||||||||&#8221; text_orientation=&#8221;center&#8221; custom_margin=&#8221;5px||||false|false&#8221; custom_padding=&#8221;|30px||30px|false|false&#8221; text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: left;\">A pharmacogenetic test examines selected genes for variants that effect the metabolism of specific medications.<\/p>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;#genetics&#8221; button_text=&#8221;Find out more&#8221; button_alignment=&#8221;left&#8221; disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_size=&#8221;18px&#8221; button_text_color=&#8221;#FFFFFF&#8221; button_bg_color=&#8221;#2495D0&#8243; 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global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; width=&#8221;1000px&#8221; max_width=&#8221;80%&#8221; custom_margin=&#8221;|auto|50px|auto||&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text content_tablet=&#8221;<\/p>\n<h3 style=%22text-align: center;%22>Pharmacogenetics enables <span style=%22color: #2495d0;%22>Personalized Medication<\/span><\/h3>\n<p>&#8221; content_phone=&#8221;<\/p>\n<h3 style=%22text-align: center;%22>Pharmacogenetics enables <span style=%22color: #2495d0;%22>Personalized Medication<\/span><\/h3>\n<p>&#8221; 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The icons show different dosages \u2013 standard dose, reduced dose and increased dose \u2013 according to individual medical needs. &#8221; title_text=&#8221;Metabolism types Measures V3&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;90%&#8221; width_tablet=&#8221;80%&#8221; width_phone=&#8221;80%&#8221; width_last_edited=&#8221;on|phone&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;0px||||false|false&#8221; custom_margin_tablet=&#8221;0px||||false|false&#8221; custom_margin_phone=&#8221;0px||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;40px||35px||false|true&#8221; border_radii=&#8221;on|15px|15px|15px|15px&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; custom_css_main_element_last_edited=&#8221;on|desktop&#8221; custom_css_main_element_phone=&#8221;@media (max-width: 768px) {|| img {|| width: 100%;|| height: auto;|| }||}&#8221; custom_css_main_element_tablet=&#8221; width: 100% !important; || height: auto !important;||&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; custom_css_main_element=&#8221;margin: auto&#8221; global_colors_info=&#8221;{}&#8221; custom_css_main_element_last_edited=&#8221;on|phone&#8221; custom_css_main_element_phone=&#8221;order:1;||&#8221; custom_css_main_element_tablet=&#8221;margin: auto&#8221;][et_pb_text disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial|700|||||||&#8221; text_text_color=&#8221;#2495D0&#8243; text_font_size=&#8221;20px&#8221; header_font=&#8221;Barlow||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;center&#8221; header_3_text_color=&#8221;#00943D&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;||-5px||false|false&#8221; custom_padding=&#8221;||0px|||&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;top&#8221; animation_intensity_slide=&#8221;12%&#8221; text_font_size_tablet=&#8221;20px&#8221; text_font_size_phone=&#8221;20px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>individualization<\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_font=&#8221;Arial||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_font=&#8221;Arial|700|||||||&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#0A0A0A&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;left&#8221; header_3_text_color=&#8221;#0A0A0A&#8221; header_3_font_size=&#8221;26px&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||10px||false|false&#8221; custom_padding=&#8221;|||&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;22px&#8221; header_2_font_size_last_edited=&#8221;on|desktop&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>How does PGx support physician?<\/h3>\n<p>[\/et_pb_text][et_pb_text content_last_edited=&#8221;off|desktop&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial||||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;18px&#8221; header_font=&#8221;Arial||||||||&#8221; custom_margin=&#8221;5px||||false|false&#8221; custom_padding_tablet=&#8221;|25px||25px|false|false&#8221; custom_padding_phone=&#8221;|25px||25px|false|false&#8221; custom_padding_last_edited=&#8221;off|desktop&#8221; text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|tablet&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>The results of a patient&#8217;s pharmacogenetic test can be used to individually adjust the <strong>selection<\/strong> and <strong>dosage<\/strong> of medication.<\/p>\n<p>This allows risks to be avoided before taking a drug or to diagnose and reduce side effects that have already occurred. This complements existing diagnostic procedures as a decision-making aid and pursues the approach of <strong>personalized medicine<\/strong>. <\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221; disabled_on=&#8221;off|off|off&#8221; module_class=&#8221;custom_row&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; vertical_offset=&#8221;0px&#8221; custom_margin=&#8221;|auto||auto|false|false&#8221; custom_padding=&#8221;0px||50px||false|false&#8221; custom_padding_tablet=&#8221;0px||50px||false|false&#8221; custom_padding_phone=&#8221;0px||50px||false|false&#8221; custom_css_free_form=&#8221;@media all and (max-width: 980px) {||\/*** wrap row in a flex box ***\/||.custom_row {|| display: -webkit-box;|| display: -moz-box;|| display: -ms-flexbox;|| display: -webkit-flex;|| display: flex;||-webkit-flex-wrap: wrap; \/* Safari 6.1+ *\/||flex-wrap: wrap;||}|| ||\/*** custom classes that will designate the order of columns in the flex box row ***\/||.first-on-mobile {||-webkit-order: 1;||order: 1;||}|| ||.second-on-mobile {||-webkit-order: 2;||order: 2;||}|| ||.third-on-mobile {||-webkit-order: 3;||order: 3;||}|| ||.fourth-on-mobile {||-webkit-order: 4;||order: 4;||}||\/*** add margin to last column ***\/||.custom_row:last-child .et_pb_column:last-child {||margin-bottom: 30px;||}|| ||}&#8221; 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background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;||-5px||false|false&#8221; custom_padding=&#8221;||0px|||&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;top&#8221; animation_intensity_slide=&#8221;12%&#8221; text_font_size_tablet=&#8221;20px&#8221; text_font_size_phone=&#8221;20px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Clinical relevance<br \/>\n[\/et_pb_text][et_pb_text disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;|700|||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;26px&#8221; header_font=&#8221;Arial||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_font=&#8221;Arial|700|||||||&#8221; header_2_text_color=&#8221;#0A0A0A&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;left&#8221; header_3_text_color=&#8221;#0A0A0A&#8221; header_3_font_size=&#8221;26px&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||10px||false|false&#8221; custom_padding=&#8221;|||&#8221; text_font_size_tablet=&#8221;26px&#8221; text_font_size_phone=&#8221;26px&#8221; text_font_size_last_edited=&#8221;on|desktop&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;22px&#8221; header_2_font_size_last_edited=&#8221;on|desktop&#8221; custom_css_main_element=&#8221;display: flex;&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>In which medical indications does pharmacogenetics play a role?<\/h3>\n<p>[\/et_pb_text][et_pb_text content_last_edited=&#8221;off|desktop&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial||||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;18px&#8221; header_font=&#8221;Arial||||||||&#8221; text_orientation=&#8221;center&#8221; custom_margin=&#8221;5px||||false|false&#8221; custom_padding_tablet=&#8221;|25px||25px|false|false&#8221; custom_padding_phone=&#8221;|25px||25px|false|false&#8221; custom_padding_last_edited=&#8221;off|desktop&#8221; text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: left;\">Pharmacogenetics plays an important role in a wide range of clinical conditions. The PGXperts system contains evidence-based data on more than <strong>150 drugs<\/strong> that are influenced by genetics <strong>(gene-drug pairs)<\/strong> and can be used for various indications. <\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_css_main_element=&#8221;margin: auto;&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/pgxperts.com\/wp-content\/uploads\/2024\/12\/Grafik_Haeufigkeit_Gene_und_Indikationen_EN-1.png&#8221; title_text=&#8221;Graphic_Frequency_of_genes_and_indications_EN_Indications_PA02&#8243; align=&#8221;right&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;95%&#8221; width_tablet=&#8221;100%&#8221; width_phone=&#8221;100%&#8221; width_last_edited=&#8221;on|tablet&#8221; module_alignment=&#8221;right&#8221; custom_margin=&#8221;||||false|false&#8221; custom_margin_tablet=&#8221;25px||||false|false&#8221; 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custom_css_percent_tablet=&#8221;margin-bottom: 0px;&#8221;][\/et_pb_number_counter][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial||||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;26px&#8221; width=&#8221;500px&#8221; max_width=&#8221;80%&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;35px||13px||false|false&#8221; custom_margin_tablet=&#8221;10px||30px||false|false&#8221; custom_margin_phone=&#8221;0px||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;0px||0px||false|false&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; text_font_size_tablet=&#8221;23px&#8221; text_font_size_phone=&#8221;22px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: center;\"><b>of the population can benefit from pharmacogenetics<\/b><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; custom_css_main_element=&#8221;margin: auto !important&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial|700|||||||&#8221; text_text_color=&#8221;#2495D0&#8243; text_font_size=&#8221;20px&#8221; header_font=&#8221;Barlow||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;center&#8221; header_3_text_color=&#8221;#00943D&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;||-5px||false|false&#8221; custom_padding=&#8221;||0px|||&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;top&#8221; animation_intensity_slide=&#8221;12%&#8221; text_font_size_tablet=&#8221;20px&#8221; text_font_size_phone=&#8221;20px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Genetic occurrence<\/p>\n<p>[\/et_pb_text][et_pb_text disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;|700|||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;26px&#8221; header_font=&#8221;Arial||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_font=&#8221;Arial|700|||||||&#8221; header_2_text_color=&#8221;#0A0A0A&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;left&#8221; header_3_text_color=&#8221;#0A0A0A&#8221; header_3_font_size=&#8221;26px&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||10px||false|false&#8221; custom_padding=&#8221;|||&#8221; text_font_size_tablet=&#8221;26px&#8221; text_font_size_phone=&#8221;26px&#8221; text_font_size_last_edited=&#8221;on|desktop&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;22px&#8221; header_2_font_size_last_edited=&#8221;on|desktop&#8221; custom_css_main_element=&#8221;display: flex;&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Personalized medication for everyone<\/h3>\n<p>[\/et_pb_text][et_pb_text content_last_edited=&#8221;off|desktop&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial||||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;18px&#8221; header_font=&#8221;Arial||||||||&#8221; text_orientation=&#8221;center&#8221; custom_margin=&#8221;5px||||false|false&#8221; custom_padding_tablet=&#8221;|25px||25px|false|false&#8221; custom_padding_phone=&#8221;|25px||25px|false|false&#8221; custom_padding_last_edited=&#8221;off|desktop&#8221; text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: left;\">A US study involving over 10,000 participants showed that 99% of people have at least one genetically relevant variant that can influence the efficacy or compatibility of medications.<\/p>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/pubmed.ncbi.nlm.nih.gov\/26947514\/&#8221; url_new_window=&#8221;on&#8221; button_text=&#8221;Find out more&#8221; button_alignment=&#8221;left&#8221; disabled_on=&#8221;off|off|off&#8221; module_class=&#8221;button1&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_size=&#8221;18px&#8221; button_text_color=&#8221;#FFFFFF&#8221; button_bg_color=&#8221;#2495D0&#8243; 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global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||40px|||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial|700|||||||&#8221; text_text_color=&#8221;#2495D0&#8243; text_font_size=&#8221;20px&#8221; header_font=&#8221;Barlow||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;center&#8221; header_3_text_color=&#8221;#00943D&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; width_last_edited=&#8221;off|phone&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;||-5px||false|false&#8221; custom_padding=&#8221;||0px|||&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;top&#8221; animation_intensity_slide=&#8221;12%&#8221; text_font_size_tablet=&#8221;20px&#8221; text_font_size_phone=&#8221;20px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Metabolization types<br \/>\n[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_font=&#8221;Arial||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_font=&#8221;Arial|700|||||||&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#0A0A0A&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;left&#8221; header_3_text_color=&#8221;#0A0A0A&#8221; header_3_font_size=&#8221;26px&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||10px||false|false&#8221; custom_padding=&#8221;|||&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;22px&#8221; header_2_font_size_last_edited=&#8221;on|desktop&#8221; header_3_font_size_tablet=&#8221;26px&#8221; header_3_font_size_phone=&#8221;22px&#8221; header_3_font_size_last_edited=&#8221;off|desktop&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>What types of metabolization are there?<\/h3>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;18px&#8221; text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|tablet&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Pharmacogenetics distinguishes between several metabolization types in order to describe the speed of a patient&#8217;s metabolism for a specific drug.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||0px|||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; custom_css_main_element=&#8221;order:2;&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb image_icon_background_color=&#8221;RGBA(255,255,255,0)&#8221; image=&#8221;https:\/\/pgxperts.com\/wp-content\/uploads\/2024\/09\/Metabolisierungs_Typen_Icon_01.png&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;100%&#8221; content_max_width_tablet=&#8221;100%&#8221; content_max_width_phone=&#8221;100%&#8221; content_max_width_last_edited=&#8221;on|tablet&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; body_font_size=&#8221;18px&#8221; background_color=&#8221;rgba(135,137,136,0.05)&#8221; custom_margin=&#8221;||10px||false|false&#8221; custom_padding=&#8221;25px|20px|25px|25px|false|false&#8221; body_font_size_tablet=&#8221;18px&#8221; body_font_size_phone=&#8221;16px&#8221; body_font_size_last_edited=&#8221;on|phone&#8221; border_radii=&#8221;on|15px|15px|15px|15px&#8221; border_width_all=&#8221;1px&#8221; border_color_all=&#8221;RGBA(135,137,136,0.09)&#8221; border_style_all_image=&#8221;none&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span style=\"color: rgba(234, 0, 0, 0.84);\"><strong>Slow metabolism<\/strong><\/span> (<strong>p<\/strong>oor <strong>m<\/strong>etabolizer) leads to excessive drug concentrations and can cause serious side effects.<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb image_icon_background_color=&#8221;RGBA(255,255,255,0)&#8221; image=&#8221;https:\/\/pgxperts.com\/wp-content\/uploads\/2024\/09\/Metabolisierungs_Typen_Icon-02.png&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;100%&#8221; content_max_width_tablet=&#8221;100%&#8221; content_max_width_phone=&#8221;100%&#8221; content_max_width_last_edited=&#8221;on|tablet&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; body_font_size=&#8221;18px&#8221; background_color=&#8221;rgba(135,137,136,0.05)&#8221; custom_margin=&#8221;||10px||false|false&#8221; custom_padding=&#8221;25px|20px|25px|25px|false|false&#8221; body_font_size_tablet=&#8221;18px&#8221; body_font_size_phone=&#8221;16px&#8221; body_font_size_last_edited=&#8221;on|phone&#8221; border_radii=&#8221;on|15px|15px|15px|15px&#8221; border_width_all=&#8221;1px&#8221; border_color_all=&#8221;RGBA(135,137,136,0.09)&#8221; border_style_all_image=&#8221;none&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>In the case of<span style=\"color: rgba(244, 171, 14, 0.84);\"> <strong>intermediate metabolizers<\/strong><\/span><span style=\"color: rgba(10, 10, 10, 0.84);\">(<strong>i<\/strong>ntermediate <strong>m<\/strong>etabolizer)<\/span> the duration of action is prolonged, and side effects are more likely.<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb image_icon_background_color=&#8221;RGBA(255,255,255,0)&#8221; image=&#8221;https:\/\/pgxperts.com\/wp-content\/uploads\/2024\/09\/Metabolisierungs_Typen_Icon-03.png&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;100%&#8221; content_max_width_tablet=&#8221;100%&#8221; content_max_width_phone=&#8221;100%&#8221; content_max_width_last_edited=&#8221;on|tablet&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; body_font_size=&#8221;18px&#8221; background_color=&#8221;rgba(135,137,136,0.05)&#8221; custom_margin=&#8221;||10px||false|false&#8221; custom_padding=&#8221;25px|20px|25px|25px|false|false&#8221; body_font_size_tablet=&#8221;18px&#8221; body_font_size_phone=&#8221;16px&#8221; body_font_size_last_edited=&#8221;on|phone&#8221; border_radii=&#8221;on|15px|15px|15px|15px&#8221; border_width_all=&#8221;1px&#8221; border_color_all=&#8221;RGBA(135,137,136,0.09)&#8221; border_style_all_image=&#8221;none&#8221; global_colors_info=&#8221;{}&#8221;]In <span style=\"color: #00943d;\"><strong>normal metabolizers<\/strong><\/span> (<strong>e<\/strong>xtensive <strong>m<\/strong>etabolizers) the drug concentration is within the therapeutic window with expected efficacy over a longer period of time.<br \/>\n[\/et_pb_blurb][et_pb_blurb image_icon_background_color=&#8221;RGBA(255,255,255,0)&#8221; image=&#8221;https:\/\/pgxperts.com\/wp-content\/uploads\/2024\/09\/Metabolisierungs_Typen_Icon-04.png&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;100%&#8221; content_max_width_tablet=&#8221;100%&#8221; content_max_width_phone=&#8221;100%&#8221; content_max_width_last_edited=&#8221;on|tablet&#8221; _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; body_font_size=&#8221;18px&#8221; background_color=&#8221;rgba(135,137,136,0.05)&#8221; custom_margin=&#8221;||10px||false|false&#8221; custom_padding=&#8221;25px|20px|25px|25px|false|false&#8221; body_font_size_tablet=&#8221;18px&#8221; body_font_size_phone=&#8221;16px&#8221; body_font_size_last_edited=&#8221;on|phone&#8221; border_radii=&#8221;on|15px|15px|15px|15px&#8221; border_width_all=&#8221;1px&#8221; border_color_all=&#8221;RGBA(135,137,136,0.09)&#8221; border_style_all_image=&#8221;none&#8221; global_colors_info=&#8221;{}&#8221;]<span style=\"color: rgba(35, 113, 209, 0.84);\"><strong>Ultrarapid metabolizers<\/strong><\/span> (<strong>u<\/strong>ltrarapid <strong>m<\/strong>etabolizers) break down an active substance too quickly, which can lead to treatment failure.[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; custom_css_main_element=&#8221;margin: auto;||order:1;&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/pgxperts.com\/wp-content\/uploads\/2024\/12\/Metabolisierungs_Typen_Gesamt_en_A.png&#8221; alt=&#8221;Metabolization types and line chart&#8221; title_text=&#8221;Metabolization types&#8221; show_bottom_space=&#8221;off&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; width_tablet=&#8221;100%&#8221; width_phone=&#8221;100%&#8221; width_last_edited=&#8221;on|phone&#8221; height_tablet=&#8221;100%&#8221; height_phone=&#8221;100%&#8221; height_last_edited=&#8221;on|tablet&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;&#8221; custom_margin_last_edited=&#8221;on|desktop&#8221; custom_padding=&#8221;||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Section&#8221; module_id=&#8221;Benefits&#8221; _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;75px|||||&#8221; custom_margin_tablet=&#8221;75px|||||&#8221; custom_margin_phone=&#8221;10px||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;50px||3px|||&#8221; da_popup_slug=&#8221;vorteile&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; width=&#8221;1000px&#8221; max_width=&#8221;80%&#8221; custom_margin=&#8221;|auto|50px|auto||&#8221; custom_padding=&#8221;0px||0px|||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text content_tablet=&#8221;<\/p>\n<h3>Optimizing complex pharmacotherapy<\/h3>\n<p>&#8221; content_phone=&#8221;<\/p>\n<h3>Optimizing complex pharmacotherapy<\/h3>\n<p>&#8221; content_last_edited=&#8221;off|desktop&#8221; disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_font=&#8221;Barlow||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_font=&#8221;Arial|700|||||||&#8221; header_2_text_color=&#8221;#0A0A0A&#8221; header_2_font_size=&#8221;44px&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;center&#8221; header_3_text_color=&#8221;#0A0A0A&#8221; header_3_font_size=&#8221;44px&#8221; header_3_line_height=&#8221;1.2em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||-1px||false|false&#8221; custom_padding=&#8221;|||&#8221; header_2_font_size_tablet=&#8221;44px&#8221; header_2_font_size_phone=&#8221;22px&#8221; header_2_font_size_last_edited=&#8221;on|phone&#8221; header_3_font_size_tablet=&#8221;44px&#8221; header_3_font_size_phone=&#8221;33px&#8221; header_3_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; header_font_size__hover=&#8221;30px&#8221; header_font_size__hover_enabled=&#8221;30px&#8221; header_letter_spacing__hover=&#8221;0px&#8221; header_letter_spacing__hover_enabled=&#8221;0px&#8221; header_text_shadow_style__hover=&#8221;none&#8221; header_text_shadow_style__hover_enabled=&#8221;none&#8221; header_text_shadow_color__hover=&#8221;rgba(0,0,0,0.4)&#8221; header_text_shadow_color__hover_enabled=&#8221;rgba(0,0,0,0.4)&#8221;]<\/p>\n<h3 style=\"text-align: center;\"><span style=\"color: #2495d0;\">Personalized Medication<\/span> <br \/>offers numerous benefits<\/h3>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Section&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||0px|||&#8221; da_disable_devices=&#8221;off|off|off&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;2&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_icon font_icon=&#8221;&#xf505;||fa||900&#8243; icon_color=&#8221;#2495D0&#8243; icon_width=&#8221;55px&#8221; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;||||false|false&#8221; custom_margin_tablet=&#8221;||||false|false&#8221; custom_margin_phone=&#8221;||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_icon][et_pb_text content_last_edited=&#8221;off|desktop&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial||||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;18px&#8221; header_font=&#8221;Arial||||||||&#8221; header_4_font_size=&#8221;26px&#8221; custom_margin=&#8221;5px||||false|false&#8221; text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|tablet&#8221; header_4_font_size_tablet=&#8221;26px&#8221; header_4_font_size_phone=&#8221;22px&#8221; header_4_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"et_pb_blurb_container\">\n<h4 class=\"et_pb_module_header\" style=\"text-align: center;\"><strong>Increased therapeutic success<\/strong><\/h4>\n<div class=\"et_pb_blurb_description\">\n<p style=\"text-align: center;\">Increased response rate and reduced risk of adverse drug reactions<\/p>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_icon font_icon=&#8221;&#xf4e9;||fa||400&#8243; icon_color=&#8221;#2495D0&#8243; icon_width=&#8221;55px&#8221; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;||||false|false&#8221; custom_margin_tablet=&#8221;||||false|false&#8221; custom_margin_phone=&#8221;||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_icon][et_pb_text content_last_edited=&#8221;off|desktop&#8221; _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial||||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;18px&#8221; header_font=&#8221;Arial||||||||&#8221; header_4_font_size=&#8221;26px&#8221; custom_margin=&#8221;5px||||false|false&#8221; text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|tablet&#8221; header_4_font_size_tablet=&#8221;26px&#8221; header_4_font_size_phone=&#8221;22px&#8221; header_4_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"et_pb_blurb_container\">\n<h4 class=\"et_pb_module_header\" style=\"text-align: center;\"><strong>Reduction of costs<\/strong><\/h4>\n<div class=\"et_pb_blurb_description\">\n<p style=\"text-align: center;\">Reduction of direct and indirect treatment costs<\/p>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_icon font_icon=&#8221;&#xf0f3;||fa||900&#8243; icon_color=&#8221;#2495D0&#8243; icon_width=&#8221;55px&#8221; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;||||false|false&#8221; custom_margin_tablet=&#8221;||||false|false&#8221; custom_margin_phone=&#8221;||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_icon][et_pb_text content_last_edited=&#8221;off|desktop&#8221; _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial||||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;18px&#8221; header_font=&#8221;Arial||||||||&#8221; header_4_font_size=&#8221;26px&#8221; custom_margin=&#8221;5px||||false|false&#8221; text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|tablet&#8221; header_4_font_size_tablet=&#8221;26px&#8221; header_4_font_size_phone=&#8221;22px&#8221; header_4_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"et_pb_blurb_container\">\n<h4 class=\"et_pb_module_header\" style=\"text-align: center;\"><strong>Early detection<\/strong><\/h4>\n<div class=\"et_pb_blurb_description\">\n<p style=\"text-align: center;\">Identifying risks of complex medications before treatment<\/p>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;2&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_icon font_icon=&#8221;&#xf21d;||fa||900&#8243; icon_color=&#8221;#2495D0&#8243; icon_width=&#8221;55px&#8221; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;||||false|false&#8221; custom_margin_tablet=&#8221;||||false|false&#8221; custom_margin_phone=&#8221;||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_icon][et_pb_text content_last_edited=&#8221;off|desktop&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial||||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;18px&#8221; header_font=&#8221;Arial||||||||&#8221; header_4_font_size=&#8221;26px&#8221; custom_margin=&#8221;5px||||false|false&#8221; text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|tablet&#8221; header_4_font_size_tablet=&#8221;26px&#8221; header_4_font_size_phone=&#8221;22px&#8221; header_4_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"et_pb_blurb_container\">\n<div class=\"et_pb_blurb_container\">\n<h4 class=\"et_pb_module_header\" style=\"text-align: center;\"><strong>Lifelong benefits for patients<\/strong><\/h4>\n<div class=\"et_pb_blurb_description\">\n<p style=\"text-align: center;\">One-time examination for a patient &amp; lifelong benefits through personalized medication<\/p>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; 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content_phone=&#8221;<\/p>\n<h3>The leadership team behind PGXperts<\/h3>\n<p>&#8221; content_last_edited=&#8221;off|desktop&#8221; disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_font=&#8221;Arial||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_font=&#8221;Arial|700|||||||&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#0A0A0A&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;left&#8221; header_3_text_color=&#8221;#0A0A0A&#8221; header_3_font_size=&#8221;26px&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||10px||false|false&#8221; custom_padding=&#8221;||0px|||&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;22px&#8221; 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_module_preset=&#8221;default&#8221; text_font=&#8221;|700|||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;26px&#8221; header_font=&#8221;Arial||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_font=&#8221;Arial|700|||||||&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#0A0A0A&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;left&#8221; header_3_text_color=&#8221;#0A0A0A&#8221; header_3_font_size=&#8221;26px&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||10px||false|false&#8221; custom_padding=&#8221;|||&#8221; text_font_size_tablet=&#8221;26px&#8221; text_font_size_phone=&#8221;22px&#8221; text_font_size_last_edited=&#8221;off|desktop&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;22px&#8221; 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text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>The origins of research into individual drug response date back to the 1950s, when genetic variations were first identified as the cause of differences in drug processing. The term was coined in 1959 by <strong>Friedrich Vogel<\/strong>, who laid the foundation for a new field of research. <\/p>\n<p>The decoding of the genome in 2003 was a milestone for personalized medicine. Technological advances and reduced costs in gene analysis and data processing now make it possible to incorporate evidence-based research findings into decisions on medication. <\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=&#8221;on&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; disabled_on=&#8221;off|off|off&#8221; module_class=&#8221;custom_row&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(36,149,208,0.1)&#8221; vertical_offset=&#8221;0px&#8221; width=&#8221;1050px&#8221; max_width=&#8221;80%&#8221; custom_margin=&#8221;||||false|false&#8221; custom_margin_tablet=&#8221;||||false|false&#8221; custom_margin_phone=&#8221;||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;40px|50px|40px|50px|false|false&#8221; custom_padding_tablet=&#8221;40px|50px|10px|50px|false|false&#8221; custom_padding_phone=&#8221;|30px|5px|30px|false|false&#8221; custom_css_free_form=&#8221;@media all and (max-width: 980px) {||\/*** wrap row in a flex box ***\/||.custom_row {|| display: -webkit-box;|| display: -moz-box;|| display: -ms-flexbox;|| display: -webkit-flex;|| display: flex;||-webkit-flex-wrap: wrap; \/* Safari 6.1+ *\/||flex-wrap: wrap;||}|| ||\/*** custom classes that will designate the order of columns in the flex box row ***\/||.first-on-mobile {||-webkit-order: 1;||order: 1;||}|| ||.second-on-mobile {||-webkit-order: 2;||order: 2;||}|| ||.third-on-mobile {||-webkit-order: 3;||order: 3;||}|| ||.fourth-on-mobile {||-webkit-order: 4;||order: 4;||}||\/*** add margin to last column ***\/||.custom_row:last-child .et_pb_column:last-child {||margin-bottom: 30px;||}|| ||}&#8221; border_radii=&#8221;on|15px|15px|15px|15px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#xf05a;||fa||900&#8243; icon_color=&#8221;#2495D0&#8243; image_icon_background_color=&#8221;RGBA(255,255,255,0)&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;65px&#8221; content_max_width=&#8221;100%&#8221; icon_placement_tablet=&#8221;left&#8221; icon_placement_phone=&#8221;top&#8221; icon_placement_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;|600|||||||&#8221; header_font_size=&#8221;18px&#8221; header_line_height=&#8221;1.3em&#8221; body_font=&#8221;||||||||&#8221; body_font_size=&#8221;18px&#8221; image_icon_custom_margin=&#8221;0px||||false|false&#8221; module_alignment=&#8221;left&#8221; custom_margin=&#8221;||3px||false|false&#8221; custom_padding=&#8221;||||false|false&#8221; header_font_size_tablet=&#8221;17px&#8221; header_font_size_phone=&#8221;17px&#8221; header_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Natural changes in the DNA sequence, known as polymorphisms, are passed down from parents to offspring. These genetic variants can effect gene function (genotype) and can change both external traits, such as eye and hair color, as well as biological processes (phenotypes). <\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Popup &#8211; #genetik&#8221; module_id=&#8221;genetics&#8221; module_class=&#8221;popup&#8221; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; da_is_popup=&#8221;on&#8221; da_popup_slug=&#8221;genetik&#8221; da_disable_devices=&#8221;off|off|off&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Desktop&#8221; _builder_version=&#8221;4.24.3&#8243; _module_preset=&#8221;default&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;|700|||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;26px&#8221; header_font=&#8221;Arial||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_font=&#8221;Arial|700|||||||&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#0A0A0A&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;left&#8221; header_3_text_color=&#8221;#0A0A0A&#8221; header_3_font_size=&#8221;26px&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||10px||false|false&#8221; custom_padding=&#8221;|||&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;22px&#8221; header_2_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3 style=\"text-align: center;\">What is analysed in pharmacogenetics?<\/h3>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=&#8221;on&#8221; disabled_on=&#8221;off|off|off&#8221; module_class=&#8221;custom_row&#8221; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; vertical_offset=&#8221;0px&#8221; custom_margin=&#8221;|auto||auto|false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; custom_css_free_form=&#8221;@media all and (max-width: 980px) {||\/*** wrap row in a flex box ***\/||.custom_row {|| display: -webkit-box;|| display: -moz-box;|| display: -ms-flexbox;|| display: -webkit-flex;|| display: flex;||-webkit-flex-wrap: wrap; \/* Safari 6.1+ *\/||flex-wrap: wrap;||}|| ||\/*** custom classes that will designate the order of columns in the flex box row ***\/||.first-on-mobile {||-webkit-order: 1;||order: 1;||}|| ||.second-on-mobile {||-webkit-order: 2;||order: 2;||}|| ||.third-on-mobile {||-webkit-order: 3;||order: 3;||}|| ||.fourth-on-mobile {||-webkit-order: 4;||order: 4;||}||\/*** add margin to last column ***\/||.custom_row:last-child .et_pb_column:last-child {||margin-bottom: 30px;||}|| ||}&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial|700|||||||&#8221; text_text_color=&#8221;#2495D0&#8243; text_font_size=&#8221;20px&#8221; header_font=&#8221;Barlow||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;center&#8221; header_3_text_color=&#8221;#00943D&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||-5px||false|false&#8221; custom_padding=&#8221;||0px|||&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;top&#8221; animation_intensity_slide=&#8221;12%&#8221; text_font_size_tablet=&#8221;22px&#8221; text_font_size_phone=&#8221;20px&#8221; text_font_size_last_edited=&#8221;off|desktop&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Investigation of SNPs<br \/>\n[\/et_pb_text][et_pb_text content_last_edited=&#8221;off|desktop&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial||||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;18px&#8221; header_font=&#8221;Arial||||||||&#8221; custom_margin=&#8221;5px||||false|false&#8221; custom_padding=&#8221;||24px|||&#8221; custom_padding_tablet=&#8221;|25px||25px|false|false&#8221; custom_padding_phone=&#8221;|25px||25px|false|false&#8221; custom_padding_last_edited=&#8221;off|desktop&#8221; text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>A pharmacogenetic analysis is carried out using DNA obtained from either a blood or saliva sample. Specific sections of the DNA are examined for genetic variants, known as SNPs (single nucleotide polymorphisms), which, based on extensive research, are known to influence the metabolism of certain medications. <\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px|||||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/pgxperts.com\/wp-content\/uploads\/2024\/10\/Kreisdiagramm.jpg&#8221; alt=&#8221;Button_PerforM_inactive&#8221; title_text=&#8221;Pie chart&#8221; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; module_alignment=&#8221;center&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;||25px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; custom_css_main_element=&#8221;margin: auto&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial|700|||||||&#8221; text_text_color=&#8221;#2495D0&#8243; text_font_size=&#8221;20px&#8221; header_font=&#8221;Barlow||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; header_3_font=&#8221;|700|||||||&#8221; header_3_text_align=&#8221;center&#8221; header_3_text_color=&#8221;#00943D&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;33px&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_margin_tablet=&#8221;0px||-5px||false|false&#8221; custom_margin_phone=&#8221;0px||-5px||false|false&#8221; custom_margin_last_edited=&#8221;on|tablet&#8221; custom_padding=&#8221;||0px|||&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;top&#8221; animation_intensity_slide=&#8221;12%&#8221; text_font_size_tablet=&#8221;22px&#8221; text_font_size_phone=&#8221;20px&#8221; text_font_size_last_edited=&#8221;off|desktop&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Focus on CYP450 enzymes<br \/>\n[\/et_pb_text][et_pb_text content_last_edited=&#8221;off|desktop&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Arial||||||||&#8221; text_text_color=&#8221;#0A0A0A&#8221; text_font_size=&#8221;18px&#8221; header_font=&#8221;Arial||||||||&#8221; custom_margin=&#8221;5px||||false|false&#8221; custom_padding_tablet=&#8221;|25px||25px|false|false&#8221; custom_padding_phone=&#8221;|25px||25px|false|false&#8221; custom_padding_last_edited=&#8221;off|desktop&#8221; text_font_size_tablet=&#8221;18px&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>The metabolism of most drugs is catalyzed by enzymes of the cytochrome P450 (CYP) system. The differences in the function of these CYP450 enzymes are the reason why the intensity and duration of effects and side effects can vary greatly from patient to patient for the same dosage of a drug. <\/p>\n<p>From a clinical point of view, <a href=\"https:\/\/flexikon.doccheck.com\/de\/CYP2B6\">CYP2B6<\/a>, <a href=\"https:\/\/flexikon.doccheck.com\/de\/CYP2D6\">CYP2D6<\/a>, <a href=\"https:\/\/flexikon.doccheck.com\/de\/CYP2C19\">CYP2C19<\/a>, <a href=\"https:\/\/flexikon.doccheck.com\/de\/CYP2C9\">CYP2C9<\/a>, <a href=\"https:\/\/flexikon.doccheck.com\/de\/CYP3A4\">CYP3A4<\/a> and <a href=\"https:\/\/flexikon.doccheck.com\/de\/CYP3A5\">CYP3A5<\/a> are particularly relevant, as they metabolize between 70 and 90% of the drugs used <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6519473\/#ref-list1\" target=\"_blank\" rel=\"noopener\">*<\/a>.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The future of drug therapyPharmacogenetics (PGx)Every human being is unique \u2013 and their response to medication is just as individual. Pharmacogenetics investigates how our genes influence the effect of drugs. This knowledge enables personalized medication, whereby the right medication in the appropriate dosage can be selected for each individual patient. This makes therapies more effective [&hellip;]<\/p>\n","protected":false},"author":12,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-51373","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Pharmacogenetics - The future of drug therapy<\/title>\n<meta name=\"description\" content=\"Pharmacogenetics studies how our genes effects the medications and enables personalized treatment.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pgxperts.com\/en\/pharmacogenetics\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pharmacogenetics - 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