Pharmacogenetic testing
PGx for healthcare professionals
Every person has a unique metabolism that is determined by genetic variants. These variants influence how drugs are processed in the body and their effectiveness.
A pharmacogenetic (PGx) test can identify these variants to be considered for treatment decisions.
Only available in Germany.
Target group
Services
Procedure
Contact
FAQ
A PGx test helps you prescribe the right medication and dosage, enabling you to prescribe Personalized Medication.
We believe in strong partnerships
Since 2018, we have been collaborating with Life & Brain and the renowned Institute of Human Genetics at the University Hospital Bonn (UKB) to conduct pharmacogenetic testing.
Target group
Who can benefit from pgx testing?
A PGx test helps you make informed treatment decisions and is particularly useful for…
Patients with planned or already existing complex polypharmacy
Medicines whose effects and tolerability are strongly influenced by pharmacogenetic factors
Patients with adverse drug reactions or insufficient response to therapy
Anyone who would like to clarify possible risks and incompatibilities as a preventive measure
PGx-Check
Check now which active substances are taken into account in the examination.
Our services
Personalized Medication for your patients
PGxProfile
Pharmacogenetic profile
The PGxProfil provides the test results for 21 genes, 113 genetic variants, and 112 active substances in a structured report — including phenotypes, clinically relevant consequences, and possible therapeutic measures.
The report also includes an easy-to-understand version that can be shared with your patients. It explains the impact of individual genetic predisposition on drug metabolism and strenghtens confidence in the therapy.
InteractionsCheck
Theory becomes reality
Register now and download the iOS/Android app.
* Licence valid for three months after activation
Procedure
A few simple steps to achieve results
1. Preparation
Download the necessary forms (declaration of consent, test order, cost coverage and information sheets).
2. Sample collection & order
Inform the patient (in Germany according to GenDG), collect blood or saliva sample, and send it to the laboratory together with the completed forms.
3. Analysis in the laboratory
Sample DNA is pharmacogenetically analyzed in the laboratory and an individual PGxProfile is generated.
4. Personalize medication
Receive PGxProfile, discuss findings with patient if necessary, and adjust medication individually – for personalized, safe, and effective therapy.
Pharmacogenetics (PGx)
Drug therapy based on the latest scientific findings
%
fewer side effects
Dr. Carina Mathey
Pharmacist
Contact
Provide your patients with Personalized Medication!
We are happy to answer your questions and assist you in ordering a PGx test for your patients.
Email: pharmakogenetik@lifeandbrain.de | Phone: +49 (0) 228 6885 424
Our services for scientific research
We also offer pharmacogenetic interpretations for clinical studies. Please contact us.
FAQ
Frequently asked, simply explained
How long does it take to get the results?
The processing time from receiving the blood or saliva sample to providing the PGxProfile is approximately two weeks.
Will the costs be covered by health insurance?
In general, the patient bears the costs of the preventive examination themselves. Under certain circumstances, the health insurance company may cover the costs if there is a diagnostic issue. We therefore recommend consulting with your health insurance company in advance and, if necessary, submitting an application for coverage of the costs.
How does the sampling process work?
You can extract the sample in two ways:
- EDTA blood sample according to your standard procedure.
- Saliva sample preferred with GenoTek Oragene OG-600
Subsequently, send the samples to the designated laboratory (address see test order).
Should a PGx test be repeated during the course of treatment?
A pharmacogenetic test is usually only necessary once in a lifetime, as genetic makeup does not change. It only needs to be repeated if new relevant genes or markers are included in the test.
Who can order a PGx test?
Any general practitioner or specialist can request a pharmacogenetic test.
Which drugs are PGx-relevant?
PGx testing is particularly useful for drugs whose efficacy and tolerability are highly dependent on genetic variations. With our Pharmacogenetics Check, you can see which active substance are included in the test.
Is PGx testing suitable for every patient?
In recipients of bone marrow, liver, or kidney transplants, the results may be distorted by the donor’s genetics. The same applies to patients who have received a blood transfusion in the last four weeks. In these cases, the test is not reliable. No pharmacogenetic testing can be performed.
How reliable are the results?
The results are based on the PGXperts database, which is regularly updated under an EN ISO 13485 certified quality management system. It contains only evidence-based information from internationally recognized sources such as CPIC, DPWG, SEFF, and PharmGKB, as well as recommendations from regulatory authorities such as the EMA, FDA, HCSC, PMDA, and SwissMedic.
Pharmacogenetics check
Check now which active substances are pharmacogenetically relevant and will be taken into account in the examination.